JKUAT Kisii CBD Centre is a Centre of Jomo Kenyatta University of Agriculture and Technology (JKUAT) located at OURU TOWERS, Kisii town near Kisii main market along Kisii-Kisumu road.

JKUAT Kisii CBD Centre began on 3 May 2010 with an enrolment of 150 students and 27 lecturers. At that time courses in three areas namely Business studies, Information Technology and science were offered. As the campus became more acceptable and competitive more courses were requested for. As a result Health sciences were introduced in September 2010. Presently the campus offers a diversity of programmes in four areas and has 81 lecturers.